Isabel F de Mera

Dra. Isabel G. Fernández de Mera

Postdoctoral assistant, SaBio (Sanidad y Biotecnología) research group. National Wildlife Research Institute IREC (CSIC-Universidad de Castilla – La Mancha). Ronda de Toledo s.n. 13071 Ciudad Real, Spain.

email

Líneas de investigación

Vector-borne pathogens and intracellular bacteria

 Rickettsial agents (Rickettsia, Ehrlichia, Anaplasma, Neorickettsia, Wolbachia, Orientia) cause a diverse spectrum of vector-transmitted diseases of humans and animals. Common vectors like ticks, mosquitoes, fleas, or lice among others, and non-haematophagous arthropods, can serve as vectors and reservoirs for these bacteria. Our work focuses on the potential reservoirs, hosts and vectors of these pathogens, as well as to identify genes that are differentially expressed during host interactions.

Mycobacterium tuberculosis complex

The M. tuberculosis complex is comprised of a group of important pathogens for both human and animals. Our current research interests are aimed at the investigation of differences in pathogenicity and transmissibility as well as cell tropism between different strains of this bacterial group.

Main model hosts and pathogens

  • Hosts: Red deer, wild boar, ticks.
  • Pathogens: Mycobacterium tuberculosis complex and vector-borne pathogens.

Selected recent publications  

    • Expression of early growth response gene-2 and regulated cytokines correlate with recovery from Guillain-Barré [...] Ver Publicación
    • Oral Vaccination with Heat Inactivated Mycobacterium bovis Activates the Complement System to Protect against [...] Ver Publicación
    • A Systems Biology Approach to the Characterization of Stress Response in Dermacentor reticulatus Tick [...] Ver Publicación
    • Spotted Fever Group Rickettsiae in Questing Ticks, Central Spain Ver Publicación
    • Lesser protein degradation machinery correlates with higher BM86 tick vaccine efficacy in Rhipicephalus annulatus [...] Ver Publicación

Research Projects  

Research results